What are chemical and pharmaceutical intermediates?

On October 30, 2020, chemical pharmaceutical intermediates are a fine chemical product used in the production process from pharmaceutical raw materials to raw materials or drugs. The synthesis of chemical drugs relies on high-quality pharmaceutical intermediates. This chemical product does not require a drug production license and can be produced in ordinary chemical factories. As long as it reaches certain levels, it can be used for the synthesis of drugs. China requires more than 2000 types of raw materials and intermediates that are matched with chemical industry every year, with a demand of over 2.5 million tons. After years of development, the chemical raw materials and intermediates required for pharmaceutical production in China can basically be matched.
There are many types of pharmaceutical intermediates, which can be divided into antibiotic drug intermediates, antipyretic and analgesic drug intermediates, cardiovascular system drug intermediates, and anticancer drug intermediates according to their application fields. There are many specific types of pharmaceutical intermediate products, such as imidazole, furan, phenolic intermediate, aromatic intermediate, pyrrole, pyridine, biochemical reagent, sulfur containing, nitrogen containing, halogen compound, heterocyclic compound, starch, mannitol, microcrystalline cellulose, lactose, dextrin, ethylene glycol, sugar powder, inorganic salt, ethanol intermediate, stearate, amino acid, ethanolamine, potassium salt, etc Sodium salts and other intermediates, etc.
In addition, in recent years, due to increasingly strict drug regulatory requirements, increasing difficulty in drug research and development, and rising prices, multinational pharmaceutical companies have gradually shifted from a "vertical integration" business model to a "development cooperation" business model in order to shorten the time to market of patented drugs, reduce research and production costs, maintain good profit margins throughout the entire drug lifecycle, and improve their own business efficiency Professional decomposition of business processes such as development and production, and outsourcing to professional institutions such as pharmaceutical contract research enterprises and pharmaceutical customization research and development production enterprises.