Introduction to Pharmaceutical Intermediates

April 1, 2020. Chemical and pharmaceutical intermediates are actually some chemical raw materials or products used in the process of drug synthesis. When used in the synthesis of some drugs, the term 'pharmaceutical intermediate' should be considered as a general term for some chemical products, such as o-nitrobenzaldehyde. It is used for the anti heart pain drug nitropyridine (heartache drug) and reduces the nitro group to an amino group to form o-aminobenzaldehyde, which can be used to synthesize quinoline ring drugs. This product is mainly used as a pharmaceutical and dye intermediate, as well as a reagent for detecting acetone.
The domestic pharmaceutical intermediate industry has entered a mature stage, and the early days when a few skilled workers could make profits have passed. There will also be no situation where a basic intermediate such as aminothiazide can supply more than a dozen drugs for production. With the development of the pharmaceutical industry, new demands for pharmaceutical intermediates will continue to emerge, such as aztreonam intermediates.
However, these new products have not yet formed a significant market demand. Currently, the pharmaceutical intermediates with a relatively high demand in China are mainly traditional series products such as aminothiazide acid, demethylaminothiazide acid, and their derivatives. New projects should be carefully considered by enterprises, and the timing of intervention should be reasonably grasped on the premise of having sufficient funds and technical strength, as well as maintaining good relationships with pharmaceutical companies; In addition, we have a good understanding of the dynamics of our domestic and international peers, as well as upstream and downstream trends, and are proactive in seizing market opportunities.